Longwu Ye, Weimin He, Liming Zhang
2011
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0
Influential Citations
177
Citations
Quality indicators
Journal
Angewandte Chemie
Abstract
Azetidine is a strained 4-membered nitrogen heterocycle and can be found in various natural products[1] and compounds of biological importance. While β-lactams, i.e., azetidin-2-ones, are a rich source of antibiotics,[2] their structural isomer, azetidin-3-ones, with the carbonyl group one-carbon removed from the nitrogen atom, have not been found in nature but could serve as versatile substrates for the synthesis of functionalized azetidines.[3]