A. Barrett, Paola Dozzo, Andrew J. P. White
Sep 2, 2002
Citations
0
Influential Citations
37
Citations
Journal
Tetrahedron
Abstract
(2S)-N-Benzoyl-2-azetidinecarboxylic acid was converted into several derivatives of (5R)-1-azabicycloheptane via lactamization of 3-((2R)-azetidine)propanoic acid, subsequent aldol reaction and reduction. The structures of three stereoisomers of (5R)-3-(hydroxy-(4-nitrophenyl)methyl)-1-azabicyclo[3.2.0]heptan-2-one were determined by X-ray crystallography.