T. S. Kumara, K. Mahadevan, H. N. Harishkumar
Jun 22, 2009
Citations
0
Influential Citations
11
Citations
Journal
Phosphorus, Sulfur, and Silicon and the Related Elements
Abstract
2-Azidocarbonyl-3-chlorobenzo[b]thiophene 3 was obtained from 3-chloro-benzo[b]thiophene-2-carbonyl chloride 1 and 3-chloro-benzo[b]thiophene-2-carboxy hydrazide 2 . The compound 3 on Curtius rearrangement with various alcohols, amines, and hydrazines afforded the corresponding carbamates 4a–b , ureas 5a–j , and semicarbazides 6a–g , respectively. Compound 2 was also utilized for the synthesis of pyrazoles 7a–c by treatment with various chalcones. The structures of the newly synthesized compounds were elucidated on the basis of IR, 1 H NMR, and mass spectral data and have been screened for antimicrobial and analgesic activities.