S. Jain, B. N. Reddy, K. S. Rao
Dec 26, 2011
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0
Influential Citations
6
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Journal
Journal of Scientific Research
Abstract
Indole-3-carboxaldehydes (1a-d) undergo condensation with ethyl cyanoacetate and malononitrile to give the acrylonitrile 2a-d and 3a-d which on reaction with hydrazine hydrate yield 3,5-diamino-5-hydroxy-4-(3-indolylmethylene)pyrazoles (4a-d) and 3-amino-5-hydroxy -4-(3-indolylmethylene)pyrazoles (5a-d), respectively. The new compounds were also screened for their antibacterial activity. Keywords : Indole-3-carboxaldehydes ; Active methylene compounds; Base; Hydrazine hydrate; Pyrazoles. © 2012 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v4i1.7821 J. Sci. Res. 4 ( 1), 273-278 (2012)