J. L. Malavolta, A. A. Souto, D. L. D. Mello
Feb 1, 2014
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Influential Citations
6
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Journal
Journal of Fluorine Chemistry
Abstract
Abstract Several new 1-(5-hydroxy-5-trifluoromethyl-1 H -pyrazol-1-yl)-3-(6-trifluoromethyl pyrimidin-4-yl)-propan-1-ones were prepared by cyclocondensation between two different 3-[6-trifluoromethyl-2-(substituted)pyrimidin-4-yl]propanoylhydrazides derived from levulinic acid and versatile 1,1,1-trifluoro-4-alkoxy-3-alken-2-ones. The structure of new propionyl-spaced bis trifluoromethylated biheterocycles was characterized based on 1 H and 13 C nuclear magnetic resonance spectroscopy and mass spectrometry data.