A. Biitseva, O. V. Gordienko, M. Kornilov
Feb 1, 2007
Citations
0
Influential Citations
3
Citations
Journal
Russian Journal of Organic Chemistry
Abstract
Abstract4-Trifluoromethyl-3,4-dihydro-1,3,5-triazino[2,1-a]isoindol-2-ones were prepared by reaction of 1-aryl-1-chloro-2,2,2-trifluoroethyl isocyanates with 3-amino-1-arylimino-1H-isoindoles in the presence of triethylamine. In some events alongside the main product isomeric 2-trifluoromethyl-2,3-dihydro-1,3,5-triazino[2,1-a]isoindol-4-ones were obtained. The regioselectivity of the reaction is affected by sterical and electronic characteristics of substituents and by temperature.