Teng Wang, Ying Dong, Li-Chen Wang
Oct 1, 2007
Citations
1
Influential Citations
13
Citations
Quality indicators
Journal
Arzneimittelforschung
Abstract
Abstract A series of 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives was prepared and examined for cardiotonic activity. The structures of these new pyridazinone derivatives were confirmed by IR, 1H-NMR and mass spectrum. The cardiotonic activities of these compounds were studied on isolated perfused toad heart and compared with the activity of levosimendan (CAS 141505-33-1). Compound 5a emerged as the most interesting compound in this series with potential car-diotonic activity.