M. Suresh, P. Lavanya, K. Vasu
2010
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0
Influential Citations
3
Citations
Journal
Journal of chemical and pharmaceutical research
Abstract
4-Aminopyrimidine-5-carbaldehyde 1 underwent facile condensation with various aromatic ketone derivatives in the presence of K2CO3 and small catalytic amount of KI in acetone was afforded corresponding 7-Substituted pyrido[2,3-d]pyrimidine derivatives 3a-j. Their chemical structures were characterized using IR, H1 NMR and Mass spectral studies. All the above compounds were screened for anti-microbial activity, anti-oxidant activity and their bioassay showed them to possess significant antimicrobial activity and anti-oxidant activity.