S. Rogers, Daniel C. Whitehead, Trey Mullikin
Sep 7, 2010
Citations
1
Influential Citations
25
Citations
Journal
Organic & biomolecular chemistry
Abstract
An 88 member library based upon the marine bacterial metabolite ethyl N-(2-phenethyl) carbamate was evaluated for bacterial biofilm inhibition against a panel of medically relevant strains. These studies culminated in the discovery of a new class of molecules capable of inhibiting the formation of S. aureus biofilms with low micromolar IC(50) values.