P. Shah
Feb 20, 2014
Citations
0
Influential Citations
2
Citations
Journal
Journal of The Korean Chemical Society
Abstract
The 4-(1H)-benzotriazoyl methyl amino benzoate 3 was prepared by Mannich reaction of benzotriazole 1, ethyl-p- aminobenzoate 2 and formaldehyde. The prepared compound 3 then react with hydrazine hydrate results in the 4-(1H)-benzot- riazoyl methyl amino benzoyl hydrazide 4. This compound on condensation with pre-prepared different ethyl 2-(2-(4-(4-sub- stituted phenyl)thiazol-2-yl)hydrazono)-3-oxobutanoates 6ad, furnished 1-(4-((1H-benzo(d) (1,2,3) triazol-1-yl)methyl amino) benzoyl)-4-(2-(4-(4-substituted phenyl)thiazol-2-yl) hydrazono)-3-methyl-1H-pyrazol-5(4H)-one 7ad. All the compounds 7ad was characterized by spectral studies. The compounds showed significant antimicrobial activity against various bacteria and fungi.