V. L. Gein, N. V. Nosova, D. D. Lezhnina
Jan 1, 2021
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Journal
Russian Journal of General Chemistry
Abstract
Abstract The reaction of 2-aryl-4-hydroxy-4-methyl-6-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate in ethanol gave 4-aryl-3,6-dihydroxy-6-methyl-4,5,6,7-tetrahydro-2H-indazole-5-carboxamides, the structure of which has been proved by IR spectroscopy, 1 H NMR and 13 C spectroscopy, as well as X-ray diffraction data. Antimicrobial and analgesic activity of the obtained compounds was studied.