S. Mehta
2013
Citations
0
Influential Citations
4
Citations
Journal
Journal of Pharmaceutical Research
Abstract
Condensation of 4-bromo-2-hydroxy benzoic acid hydrazide (1) with aromatic aldehydes to gives the corresponding 4-bromo-2-hydroxy benzoic acid arylidene hydrazides (2a-h). Cyclocondensation of compounds 4-bromo-2-hydroxy benzoic acid arylidene hydrazides (2a-h) with maleic anhydride and succinic anhydride yields respectively 1-(4bromo-2-hydroxybenzamido)-5-oxo-2-aryl-2,5-dihydro-1H-pyrrole-3carboxylic acid (3a-h) and 1-(4-bromo-2-hydroxybenzamido)-5-oxo-2arylpyrrolidine-3-carboxylic acid (4a-h). The structures of these compounds were established on the basis of analytical and spectral data. All the newly synthesized compounds were evaluated for their antibacterial and antifungal activities.