I. Awad, A. Abdel-rahman, E. A. Bakhite
Mar 1, 1991
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Influential Citations
16
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Journal
Phosphorus Sulfur and Silicon and The Related Elements
Abstract
Abstract Alkylation of 2-mercapto-3-cyano-4-aryl-5,6,7,8-tetrahydroquinoline (I) gave compounds II–IV. Cyclization of III and IV afforded thienoquinolines V and VI respectively. On diazotization of V and VI, the corresponding triazinone derivatives VII and VIII were obtained. Also, reaction of V with benzoyl chloride yielded the tetracyclic compound IX. Structures of the new compounds were established by their elemental analyses and spectral data. Some of these compounds were screened in vitro for their antibacterial activities.