R. Patel, P. Desai, K. R. Desai
Sep 30, 2003
Citations
0
Influential Citations
12
Citations
Journal
ChemInform
Abstract
2-[4-(4-Chlorophenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-ylamino]-4,6-dichloro-s-triazine (2), derived from 2-amino-4-(4-chlorophenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidine (1) and 2,4,6-trichloro-1,3,5-s-triazine, on treatment with morpholine gave 2-[4-(4-chlorophenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-ylamino]-4-(morpholino)-6-chloro-s-triazine (3). Compound 3 when reacted with different arylthioureas in the presence of weak base gave new 2-[4-(4-chlorophenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-ylamino]-4-(morpholino)-6-(arylthioureido)-s-triazines (4a-j). The compounds were screened for their antibacterial, antifungal and antitubercular activities.