Dong Sung Kim, K. Kang, Kyung Seok Lee
Mar 3, 2009
Citations
0
Influential Citations
7
Citations
Journal
ChemInform
Abstract
E-mail: ssyoon@chem.skku.ac.krReceived July 31, 2008The synthesis of new 5-cyano-1,1-disubstituted phthalans having aromatic and aminoalkyl groups at C-1position of phthalan ring and their biological evaluation are described. Most compounds exhibited comparableejaculation-retarding effects to citalopram. Of these compounds, 3a, e showed excellent efficacy in delayingejaculation. Key Words : Premature ejaculation, Phthalans, EfficacyIntroductionPremature ejaculation (PE)