H. Waldmann, Yu-Peng He, Hao Tan
Nov 7, 2008
Citations
0
Influential Citations
23
Citations
Journal
Chemical communications
Abstract
A total synthesis of the biaryl antibiotic biphenomycin B is reported which makes use of three independent building blocks (key steps were a clean Suzuki-Miyaura coupling of a free acid iodide, a novel 4-hydroxyornithine synthesis, and a high-yielding macrolactamization); a practical deprotection protocol allowed isolation of the target compound with excellent recovery and purity.