I. Gracheva, A. I. Tochilkin
Mar 1, 1980
Citations
0
Influential Citations
3
Citations
Journal
Chemistry of Heterocyclic Compounds
Abstract
Abstract8-Methylquinoline-5-carboxylic acid was obtained by the Skraup reaction from 3-amino-p-toluic acid or by hydrolysis of 5-cyano-8-methylquinoline. The latter was synthesized by the Rosenmund-von Braun reaction from 5-bromo-8-methylquinoline, which was obtained by bromination of 8-methylquinoline in the presence of silver sulfate. Bromination in the side chain of 8-methylquinoline-5-carboxylic acid and its nitrile was studied.