C. Tan, J. Er, Y. Yeung
Feb 5, 2014
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0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The asymmetric cyclization of 4,4-disubstituted 3-butenoic acids is studied. Amino-thiocarbamates are used as the catalysts and N-bromosuccinimide is used as the stoichiometric halogen source. The resulting γ-butanolide products are readily converted into the corresponding γ-butenolides (up to 58% ee) derivatives in one-pot.