S. Hays
Apr 1, 1987
Citations
0
Influential Citations
2
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
3-[4-]4-(3-Methylphenyl)-1-piperazinyl[butyl]-2,4-imidazolinedione, CI-926 (1), and 3-[4-4-(3-ethoxyphenyl)-1-piperazinyl]butylamino-5,5-dimethyl-2-cyclohexen-1-one, CI-927 (2) are new antihypertensive agents which have been carbon-14 labeled in three steps starting from ethylene-14C2 oxide (5). The overall radiochemical yields for 1 and 2 were 69% and 66% respectively. The specific activity for both compounds was initially 22.6 mCi/mmol before final dilution.