E. Opozda, W. Łasocha, B. Włodarczyk-Gajda
Feb 20, 2006
Citations
0
Influential Citations
12
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract 3,4-Diaminopyridine reacts with 3-ethoxyvinylidene-2,4-pentanedione to form mainly the product of 1:2 substitution 1. 3-{[(4-Aminopyridin-3-yl)amino]methylene}pentene-2,4-dione 2 is isolated as the monosubstitution product. Reaction of this ‘half-unit’ with salicylaldehyde results in the formation of the unsymmetrical Schiff base 3. The molecular structure of 3-{[(4-Aminopyridin-3-yl)amino]methylene}pentene-2,4-dione 2 has been determined by the single crystal X-ray method. Compound 2 forms intermolecular hydrogen-bonded dimers in the crystalline state. The crystal structure of 2 has clearly established that the reaction occurs at the amino group at 3-position of pyridine ring. The dominant tautomeric form of the compounds in solution has been established.