Y. Murthy, G. Durga, A. Jha
Oct 18, 2012
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Journal
Medicinal Chemistry Research
Abstract
Abstract2-Aminobenzimidazole was diazotized and made to react with active methylene compounds viz: ethylcyanoacetate and malanonitrile. The ligands [IIIa and IIIb] were isolated, characterized, and then condensed with Ni(II) chloride, Cu(II) chloride, and Ag(I) nitrate. The ligands and complexes were characterized by elemental analysis, IR, 1H NMR, ESR, UV–Visible spectral techniques, and along with thermal studies. The antimicrobial activity of the ligands [IIIa (C12H11N5O2) and IIIb (C10H6N6)] and their metal complexes [IVa–IVf] against bacterial strains and fungal strains were investigated. The antimicrobial activity of the above metals and the ligands were discussed.