S. Saeed, N. Rashid, Muhammad Ali
Sep 29, 2010
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Influential Citations
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Journal
European Journal of Chemistry
Abstract
Nickel and copper metal complexes of N-(R-carbamothioyl)-4-nitrobenzamide (R = diphenyl and ethylbutyl) were synthesized and characterized by IR, 1 H NMR, mass spectrometry and elemental analysis. The spectroscopic data are consistent with the ligand and the metal complexes containing two O and S chelated ligands. N-(diphenylcarbamothioyl)-4-nitrobenzamide, HL 1 , was characterized by a single crystal X-ray diffraction study. It crystallizes in the triclinic space group P with unit cell dimensions of a = 6.8044(4) A, b = 10.0113(6) A, c = 13.2365(8) A, α = 6.8044(4) °, β = 78.171(4) °, γ = 13.2365(8)°, V = 882.43(9) A 3 . The ligands coordinate as bidentates yielding essentially neutral complexes of the type [ML 2 ]. The ligands and complexes were screened for their in vitro antibacterial activities and comparatively the complexes showed greater antibacterial efficacy than the thiourea derivative ligands.