J. Sweet, J. Cavallari, W. Price
Jan 23, 1997
Citations
0
Influential Citations
27
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract We present a modular synthesis of a new class of chiral N,N-chelating ligands containing the C2-symmetrictrans-2,5-disubstituted pyrrolidine moiety linked to a pyridine ring. (−)-2-[(2R,5R)-2,5-Dimethylpyrrolidin-1-ylmethyl]pyridine (11, (R,R)-MePMP), (−)-2-[2-((2R,5R)-2,5-dimethylpyrrolidin-1-yl)ethyl]pyridine (12, (R,R)-MePEP), and (+)-2-[(2R,5R)-2,5-diphenylpyrrolidin-1-ylmethyl]pyridine (13, (R,R)-PhPMP) have been prepared. The X-ray structure of the (η3-allyl)Pd complex of (R,R)-MePMP (11) is reported.