Venkata Ramakrishna Mallemula, Venkata Ramakrishna Mallemula, N. N. Sanghai
Apr 1, 2015
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Influential Citations
17
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Journal
Research on Chemical Intermediates
Abstract
The increasing clinical importance of drug-resistant fungal and bacterial pathogens has stimulated microbiological research into and development of new antimicrobial agents. Hence, in this study, we synthesized novel series of 2-(pyridin-3-yl)-1H-benzo[d]imidazoles and 2-(pyridin-3-yl)-3H-imidazo[4,5-b]pyridine derivatives. The structures of the compounds were confirmed by spectral and CHN analysis. The compounds were examined for in-vitro antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis), Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa), and the fungus Candida albicans.Graphical Abstract