J. Patel
Feb 7, 2018
Citations
0
Influential Citations
2
Citations
Journal
International Journal for Advance Research and Development
Abstract
The synthesis of 3 -(1'- phenyl- 3'-aryl -1H-pyrazol -4'-yl) furo[3,2-c]coumarins (4a-f) and 2-methyl-3-(1'–phenyl-3'-aryl-1H-pyrazol-4'-yl)furo- [3,2-c]coumarins (5a-f) has been carried out by the reaction of various 4-hydroxy coumarins (1a-c) with appropriate 2-(1-phenyl-3-aryl-1H- pyrazol-4-yl)-1-nitro-ethenes (2a-b) and 1-(1-phenyl-3-aryl-1H-pyrazol-4-yl)-2-nitro propenes (3a-b) respectively in the presence of catalytic amount of piperidine in refluxing methanol. All the synthesized compounds (4a-f) and (5a-f) were screened for their antimicrobial activity.