P. Desai, D. V. Parekh
2021
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Abstract
2amino propionic acid (Alanine), is extensively used as complex-forming reagents. Alanine was condensed with 1(5-benzoyl-1H-1,2,3 benzotriazole-1-yl) 2-chloroethanone and yield 2-{[2-(5-benzoyl-1H-1,2,3 benzotriazole-1-yl) 2-oxoethyl]amino} propionic acid.The newly synthesized ligands and their complexes with first transitions series metal had been prepared, were analyzed and characterized by using different techniques, such as elemental analysis, infrared and electronics spectra. The IR spectra, NMR spectra and atomic absorption analysis show that the benzotriazole ligand forming chelates with 2:1 (Ligand: Metal) stoichiometry. Metal complexes were evaluator invitro antibacterial activity against Negative and Positive bacteria. The complexes showed significant antibacterial activity.