I. Kolev, S. Petrova, R. Nikolova
Feb 27, 2013
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Influential Citations
3
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract This work describes the synthesis of 2-iodo-3,4,5-trimethoxybenzoic acid. The combination of iodine and silver trifluoroacetate (AgTFA) reagents was used successfully for the iodination of 3,4,5-trimetoxybenzoic acid. To improve the efficiency of the synthetic process a significant modification on the experimental design was also performed. The main structural features of the obtained aryl iodide were investigated by a single crystal X-ray diffraction analysis, FTIR, 1 H and 13 C NMR spectroscopy.