Ratika Sharma, M. Sapnakumari, B. Narayana
Dec 28, 2013
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0
Influential Citations
2
Citations
Journal
European Chemical Bulletin
Abstract
The title compound 3'-[(4-fluorophenyl)carbonyl]-5'-(hydroxymethyl)-4’-phenyl spiro[indole-3,2'-pyrrolidin]-2(1 H )-one is synthesized by the straightforward multicomponent reaction of 1-(4-fluorophenyl)-3-phenylprop-2-en-1-one, isatin and serine, and is crystallises in monoclinic space group C2/c.The molecule is essentially planar except one of the pyrrolidin ring which adopts normal envelope conformation. The supermoleular assembly is consolidated by ᴨ-ᴨ interactions [centroid- centroid distance= 3.7983(18)]. The crystal structure is stabilized by one C-H…O intra-hydrogen bond, two N-H…O and one O-H…N inter-hydrogen bonds, and these interactions links the molecules into chain extending along the b-axis.