Qingguo Meng, Wenqiang Tan, G. Hou
Dec 24, 2013
Citations
1
Influential Citations
11
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract Two epimers, 20S,24R-epoxy dammarane-3β,12β,25-triol (3) and 20S,24S-epoxy dammarane-3β,12β,25-triol (4) were prepared from 20(S)-protopanaxadiol, which were confirmed by ESI-MS, NMR, and X-ray single-crystal diffraction. The results indicate the configuration of C-24 of 3 and 4 are R-form and S-form, respectively. 3 and 4 crystallize in a orthorhombic space group P2(1)2(1)2(1). Compound 3 have more complicated intramolecular hydrogen bonds than that of 4, which results in the weaker molecular polarity in 3. Crystal stacking displays that 3 generates a H-bonded tube with left-handed chiral channel, while 4 extends into two-dimensional network with right-handed and left-handed chiral channels in the solid state.