N. R. Thimmegowda, S. Swamy, S. Swamy
2008
Citations
1
Influential Citations
51
Citations
Quality indicators
Journal
Bioorganic & medicinal chemistry letters
Abstract
A novel series of trisubstituted benzimidazole and its precursors (3-7) were synthesised and characterized by using 1H NMR, LC/MS, FTIR and elemental analysis techniques. The title compounds were evaluated for inhibition against MDA-MB-231 breast cancer cell proliferation. The results revealed that the compound N-(4-cyano-3-(trifluoromethyl) phenyl)-4-fluoro-3-nitrobenzamide (3) was the potent inhibitor.