M. Pankaj, S. Vikas, K. Minu
Dec 1, 2015
Citations
0
Influential Citations
2
Citations
Quality indicators
Journal
The Pharma Innovation Journal
Abstract
The review of literature showed that cinnoline derivatives were found to elicit many pharmacological actions like anti-hypertensive, antithrombotic, antihistamine, antileukemic, CNS activity, anti tumor, antibacterial and antisecretory activity.In the substituted Cinnoline thiophene series, the compounds which are halogen mainly Chloro, Bromo and Fluoro Substituted were showed potent antibacterial, anti-inflammatory and anti-fungal activity than other compounds. Especially Chloro Substituted Compounds Showed more potent antimicrobial activity and anti-inflammatory activity among all the substituted cinnoline thiophene compounds.