Zeba N. Siddiqui, Farheen Farooq, T. N. M. Musthafa
Apr 1, 2013
Citations
3
Influential Citations
68
Citations
Quality indicators
Journal
Journal of Saudi Chemical Society
Abstract
Abstract Two novel halopyrazole derivatives ( 3 , 5 ) were synthesized from 5-chloro-3-methyl-1-phenylpyrazole-4-carboxaldehyde ( 1 ) using appropriate synthetic routes. Newly synthesized compounds were characterized using elemental analysis, spectral data (IR, 1 H NMR, 13 C NMR and mass spectrometry) and were evaluated for their in vitro antimicrobial activity. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) were determined for the test compounds as well as for reference standards. The investigation of antimicrobial screening revealed that compounds ( 3 , 5 ) showed good antibacterial and antifungal activities, respectively.