A. Ahmadi
Sep 22, 2014
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Influential Citations
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Quality indicators
Journal
Bulletin of The Chemical Society of Ethiopia
Abstract
In the present study, synthesis, and biological evaluation of some novel derivatives of 2-bromomethyl-benzimidazole were investigated. The structures of the new synthesized compounds were characterized by IR, 1 H-NMR, 13 C-NMR, mass spectrometry and elemental analysis and screened for antimicrobial activity against two Gram-positive strains ( Staphylococcus aureus and Bacillus subtilis) and two Gram-negative strains ( Escherichia coli and Pseudomonas aeruginosa) . Results indicate that new compounds showed moderate to good activity when compared with standard antibiotic Ciprofloxacin and Streptomycin. KEY WORDS : Benzimidazole, Antibacterial activity, Bromo derivatives, Gram-positive strains, Gram-negative strains Bull. Chem. Soc. Ethiop. 2014 , 28(3), 451-456. DOI: http://dx.doi.org/10.4314/bcse.v28i3.14