Tobias Biletzki, Thomas Elschner, Toni Neuwirth
Jul 15, 2012
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0
Influential Citations
2
Citations
Journal
Arkivoc
Abstract
Diphenylbutane-1,4-diamine is prepared from 2,3-diphenylsuccinonitrile via the corresponding bis-acetamide. High level DFT-calculations show that the meso form of the diamine is stabilized by intramolecular hydrogen bo nds compared to the chiral stereoisomers. Imines are obtained in high yields by condensation of the diamine with the corresponding aldehydes. Two of the imines have been characterize d by X-ray diffraction. In both structures the meso form is observed. Imines derived from cinnamaldehyde derivatives are transformed to bis- γ-lactams by the ruthenium catalyzed reaction with C O and ethylene.