Liangde Lu, Zhong Yu, Z. Fang
Jul 1, 2012
Citations
0
Influential Citations
0
Citations
Journal
Advanced Materials Research
Abstract
An efficient method is described for the synthesis of 2-methoxy-thieno[2,3-d]pyrimidin- 4(3H)-one (5) via Gewald reaction, a tandem aza-Wittig reaction and cyclization process. The key step is an aza-Wittig reaction between iminophosphorane (2), 4-chlorophenyl isocyanine and nucleophilic reagent CH3OH. Its structures were determined by means of MS, IR and 1H NMR spectra.