Tang Jiel
2013
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Journal
Journal of Guangdong Pharmaceutical University
Abstract
Objective To design and synthesis 7,8-dimethoxy-2(1H)-quinolinone-3-formic acid methyl ester.Methods Vanillin as raw material,the target product was synthesized by the acetylation reaction,nitrification reaction,methylation reaction,reduction reaction and condensation reaction.Results 7,8-dimethoxy-2(1H)-quinolinone-3-formic acid methyl ester was synthesized and its structure was characterized by1H-NMR、13CNMR and IR.Conclusion 7,8-dimethoxy-2(1H)-quinolinone-3-formic acid methyl ester is a new quinolone derivatives with potential pharmacological activity,which has never been reported.