Shen Jun-ju
2004
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Journal
Chinese Journal of Synthetic Chemistry
Abstract
In order to find a new kind of potent fasciolicide, five derivatives of N-aryl-o-hydroxybenzenesulfonamide were synthesized from halogenated phenols first through sulfochlorination using ClSO 3H/SOCl 2 mixture as the reagent of sulfochlorination of phenols and then through amidation by refluxing the halogenated o-hydroxy-benzenesulfonyl chlorides and substitued 4-amino-diphenyl ketones or 4-amino-diphenyl ethers in dimethyl benzene. The compounds were characterized by the elemental analysis, IR and 1H NMR.