Heping Yan, Gui-ping Ouyang
Sep 1, 2013
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Journal
Advanced Materials Research
Abstract
Four compounds of 7-(3- (substituted-phenoxy) propoxy) quinazoline compounds, including 7-(3-(2,4-dichlorophenoxy) propoxy)-N-(3-chlorophenyl)-6-methoxyquinazolin-4-amine, 7-(3-(2-chlo-rophenoxy) propoxy)-N-(3-chlorophenyl)-6-methoxyquinazolin-4-amine, 7-(3-(4-chlorophenoxy) prop-oxy)-N-(3-chlorophenyl)-6-methoxyquinazolin-4-amine, 7-(3-(naphthalen-3-yloxy) propoxy)-N-(3-chl-orophenyl)-6-methoxyquinazolin-4-amine, were synthesized from N-(5-(3-chloropropoxy)-2-cyano-4-methoxyphen-yl)-N, N-dimethylformamidine by cyclization,etheration, in the yield of 45.9%50.6%56.34% and 80.6% respectively. Their structures were characterized by IR, 1H NMR, 13C NMR, MS and elemental analysis.