F. Wei, Ye Kaiqi, Jiang Yang
Aug 1, 2019
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Journal
Chemical Research in Chinese Universities
Abstract
Adamantane and its derivatives have been introduced into many drugs for current clinical research and some of them are used for the treatment of neurological disease and/or used as the antiviral agents as well as the agents against type-2 diabetes. Recently, there have been many relevant research reported for developing medicinal chemistry by employing the adamantyl group. In this paper, a new adamantane-based compound (3-phenyl-adamantane-1-carboxylic acid, PACA) was synthesized and characterized by X-ray diffraction(XRD), thermogravimeric analysis(TGA), Fourier transform infrared spectroscopy(FTIR), etc., which should be a beneficial complement or extension to the existing adamantyl-based materials.