O. Petrova, V. Lipson, L. L. Zamigailo
Dec 24, 2015
Citations
1
Influential Citations
6
Citations
Journal
Russian Journal of Organic Chemistry
Abstract
Reactions of 5-amino-3-methylpyrazole with arylglyoxals and indane-1,3-dione afforded 4-aroyl-3-methyl-4,10-dihydroindeno[1,2-b]pyrazolo[4,3-e]pyridin-5(2H)-ones, and their chemical behavior was studied in reactions with alkylating, acylating reagents and hydrazine hydrate. In three-component condensations involving 5-amino-3-methyl-1-phenylpyrazole the intermediate Michael adducts were isolated, 2-[1-(5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-oxo-2-(aryl)ethyl]-1H-indene-1,3(2H)-diones that underwent cyclization into 4-aroyl-3-methyl-1-phenylindeno[1,2-b]pyrazolo[4,3-e]pyridin-5(1H)-ones.