Robert J. Smith, Duong Nhu, Mitchell R Clark
May 4, 2017
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0
Influential Citations
21
Citations
Journal
The Journal of organic chemistry
Abstract
A tandem deprotection-cyclization reaction of 1,1-diacylcyclopropanes is described which allows rapid access to structurally diverse 2,3-disubstituted chromones in good yields, and with straightforward purification. The utility of this reaction is showcased by the construction of the potent antibacterial marine natural product bromophycoic acid E scaffold.