M. Spasova, V. Kortenska-Kancheva, Iskra Totseva
May 1, 2006
Citations
0
Influential Citations
39
Citations
Journal
Journal of Peptide Science
Abstract
Fifteen amides of cinnamic, ferulic and sinapic acids with natural and unnatural C‐protected amino acids have been synthesized. The amides (E)‐N‐(feruloyl)‐L‐tyrosine methyl ester (10), (E)‐N‐(feruloyl)‐L‐phenylalanine t‐butyl ester (11), (E)‐N‐(sinapoyl)‐L‐tyrosine methyl ester (13) and (E)‐N‐(sinapoyl)‐L‐phenylalanine t‐butyl ester (15) with a free carboxyl group of amino acids have been found in nature. The rest of the compounds are unknown. The hydroxycinnamoyl amino acid conjugates have been studied for their antioxidant activity (AOA) in bulk phase lipid autoxidation. The highest AOA has been found for the compounds 11 and 15, which contain the same phenylalanine moiety. Copyright © 2005 European Peptide Society and John Wiley & Sons, Ltd.