Subramanian Rajkumar, S. Antony Savarimuthu, R. Senthil Kumaran
Feb 2, 2016
Citations
0
Influential Citations
28
Citations
Journal
Chemical communications
Abstract
Ruthenium-catalyzed simple, cascade and one-pot synthesis of cinnoline-fused diones has been carried out by the C-H activation of phthalazinones/pyridazinones accomplished by the unusual deoxygenation of propargyl alcohols. The bond selectivity is accredited to the traceless directing nature of the hydroxyl group of propargyl alcohol. A sequential C-H activation, insertion and deoxy-oxidative annulation has been proposed based on the preliminary mechanistic study.