E. G. Nolen, Micah M Watts, D. Fowler
Oct 5, 2002
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0
Influential Citations
15
Citations
Journal
Organic letters
Abstract
[formula: see text] The stereoselective preparation of C-linked D-gluco- and D-galactopyranosyl L-serines in their alpha and beta forms is herein reported. The syntheses require the conversion of the allyl C-glycopyranosides into their iodoethyl derivatives, which then undergo substitution with the Williams' chiral glycine enolate equivalent. Deprotection and acetylation affords Boc-protected amino acids for peptide synthesis.