D. Lehmann, R. Eckardt, G. Faust
1980
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Journal
Die Pharmazie
Abstract
It is reported of the synthesis of 1-phenoxy-2-hydroxy-3-aminopropane derivatives with different substituents in the phenoxy residue as well as in the amino group. The potency and the efficacy of these derivatives depend on the substituents. By the introduction of the arylamino-ethyl residue into the nitrogen atom, beta-adrenergic locking agents with marked agonistic activity are obtained.