T. Korošec, J. Grdadolnik, U. Urleb
Jan 20, 2006
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0
Influential Citations
4
Citations
Journal
The Journal of organic chemistry
Abstract
[reaction: see text] A novel synthetic route was developed for 2-{[2-(3,4-dichlorophenyl)ethyl]propylamino}-1-pyridin-3-ylethanol (4). A dynamic process due to nitrogen inversion at the central amine nitrogen has been identified by NMR spectroscopy for the dihydrobromide salt of this compound. The conformational properties of the diastereomeric pair were determined by analysis of NOE connectivities and MO calculations.