Lu Jiu-fu, Ge Hong-guang, Zhang Hui
Apr 1, 2015
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Influential Citations
4
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Journal
Journal of Chemical Research
Abstract
The crystal structure of 5-chloro-3-(2,4-dichlorophenyl)-N-(3-methoxyphenyl)-2-methyl-6-phenylpyrazolo[1,5-a]pyrimidin-7-amine (C26H19Cl3N4O, Mr = 509.80) has been synthesised by chlorination and aminisation from 3-(2,4-dichlorophenyl)-2-methyl-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diol. Its structure was confirmed by element analysis, IR, 1H NMR and X-ray diffraction. The crystal belongs to the triclinic system, space group P-1 with a = 10.979(2) Å, b= 11.339(2) Å, c= 11.646(2) Å, a= 98.58(3) °, β= 110.21(3) °, γ= 111.61 (3) °. In addition, the compound possesses moderate anticancer activity.