Sijia Xue, Wangdong Bian, A. Chan
Aug 1, 2008
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Influential Citations
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Journal
Chinese Journal of Chemistry
Abstract
The title compound N-(4-methylbenzamido)-N′-[5-(2-trifluoromethylphenyl)-2-furoyl]thiourea has been synthesized for the first time and its crystal structure (C21H16F3N3O3S, Mr=447.43) has been determined by single-crystal X-ray diffraction analysis. The crystal belongs to monoclinic, space group P-1 with a=0.9677(7) nm, b=1.0461(8) nm, c=1.0771(7) nm, β=98.912(6)°, V=1.0083(12) nm3, Z=2, Dc=1.474 g/cm3, µ=0.22 mm−1, F(000) =460, R=0.0445 and wR=0.194 for 3504 unique reflections with 2598 observed ones [I>2δ(I)]. In the crystal structure, there are some intra- and intermolecular hydrogen bonds and C–H··· interaction between the molecules, which stabilize the crystal structure. The preliminary bioassay shows that the title compound exhibits good fungicidal activities against Fusarium oxysporium, Botrytis cinereapers, and Dothiorella gregaria.