Guodong Yin, Hou Shi, Liqianyun Xu
Jan 3, 2013
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Influential Citations
17
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Journal
Synthesis
Abstract
A selective synthesis of 4 H -chromenes by the reactions of 2-hydroxychalcone derivatives with acetonitriles substituted with electron-withdrawing groups is described. Under catalyst-free conditions, the reactions give cyano-functionalized 2-aryl-4 H -chromenes, whereas in the presence of sodium bicarbonate, 2-amino-4 H -chromene-3-carbonitriles are obtained in excellent yields.