D. Letham, H. Young
1971
Citations
0
Influential Citations
11
Citations
Journal
Phytochemistry
Abstract
Abstract A series of N-(purin-6-yl)amino acids have been synthesized. The cytokinin activities of these purines have been determined in the excised radish cotyledon bioassay and compared with the activities of related compounds lacking a carboxyl group. Cytokinin activity was greatly reduced by the presence of an unesterified carboxylic acid group in the substituent of a 6-(substituted amino)purine. The purinylamino acid which showed greatest activity was N-(purin-6-yl)-α-phenylglycine; the activity of this compound did not appear to be the consequence of conversion to 6-benzylaminopurine. The recently isolated amino acid 2-amino-5-methylhex-4-enoic acid, which was obtained as a synthetic intermediate, inhibited growth in several bioassays.